SPE Cartridge, ISOLUTE HCX- 3 Description Mixed-mode C18 and strong cation exchange functionalized silica. Manufactured using trifunctional silanes. Non end-capped. Average Particle Size 50 µm Nominal Porosity 60 Å Comments Alternative to ISOLUTE HCX where more rententive non-polar sorbent is required for rentention of polar compounds. Chemistry Data Sheet TN125_Mixed-mode_ BasicDrugs_BioFluids.pdf Materials Safety Data Sheet 905 ISOLUTE HCX-3 Product Information ISOLUTE HCX -3 page 50.pdf Chemical structure ISOLUTE HCX-3 combins C18 (Octadecyl) and sulfonic functionalities